Documentation

Interfaces

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Interfaces

AlternateGeneticCodeTranslatorInterface
Interface AlternateGeneticCodeTranslatorInterface - translates a codon under a specific NCBI genetic code table (see GeneticCodeTable::SUPPORTED_TABLES). Only the single-letter amino acid output SequenceInterface::translateCodon()'s format=1 already uses is supported here ; the 3-letter format has no current caller and was left out to keep this service's scope tight.
ChaosGameRepresentationInterface
Interface ChaosGameRepresentationInterface - the computation behind a CGR and an FCGR image, with no drawing : the points of the chaos game, and the counts of the oligonucleotides on their grid.
CodonAdaptationIndexInterface
Interface CodonAdaptationIndexInterface - scores how well a coding sequence's own codon choices match a reference organism's preferred codons (Sharp & Li, 1987), useful for predicting or optimizing how well a cloned insert is likely to express in a given host.
CodonOptimizerInterface
Interface CodonOptimizerInterface - the inverse of CodonAdaptationIndexCalculator : rather than scoring an existing coding sequence against a reference codon usage table, this picks, for each residue of a target protein, the synonymous codon with the highest count in that table - the coding sequence a perfect (CAI = 1) translation of the protein would have.
CodonUsageTableBuilderInterface
Interface CodonUsageTableBuilderInterface - builds a CodonUsageTable by counting codon occurrences across a set of real coding sequences (typically the highly expressed genes of a host organism).
CpGIslandFinderInterface
Interface CpGIslandFinderInterface - finds CpG islands using the classic Gardiner-Garden & Frommer (1987) criteria : GC content and observed/expected CpG ratio both above a threshold, over a sliding window.
MeltingTemperatureInterface
Interface MeltingTemperatureInterface
OligosInterface
Interface OligosInterface
OrfFinderInterface
Interface OrfFinderInterface - finds every open reading frame across all six reading frames (three forward, three reverse) of a DNA sequence.
ProteinPropertiesInterface
Interface ProteinPropertiesInterface
SkewCalculatorInterface
Interface SkewCalculatorInterface
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